Hillary Lum
| Years in MSTP | 2000-2008 |
| PhD | Cellular and Molecular Biology |
| Mentor | Paul Sondel |
| Thesis | Antittumor Effects by Macrophages Activated with an Agonist Monoclonal Antibody to CD40 |
| Residency | Medicine, University of Pittsburgh |
Publications
Johnson EE, Yamane BH, Buhtoiarov IN, Lum HD, Radmilvich AL, Mahvi DM, Gillies SD, Sondel PM. 2009. Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma. Clin Cancer Res 15:4875-84. PMCID: 2735865
Johnson EE, Lum HD. Rakhmilevich AL, Schmidt BE, Furlong M, Buhtoiarov IN, Hank JA, Raubitschek A, Colcher D, Reisfeld RA, Gillies SD, Sondel PM. 2008. Intratumoral immunocytokine treatment results in enhanced antitumor effects. Cancer Immunol Immunother 57:1891-902. PMCID: 2574976
Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. 2006. Tumoristatic effects of anti-CD40 mAb-activated macrophages involve nitric oxide and tumour necrosis factor-alpha. Immunology 118:261-7.
Lum HD, Buhtoiarov IN, Schmidt BE, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. 2006. In vivo CD40 ligation can induce T-cell-independent antitumor effects that involve macrophages. J Leukoc Biol 79:1181-92.
Buhtoiarov IN, Lum HD, Berke G, Sondel PM, Rakhmilevich Al. 2006. Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects. J Immunol 176:309-18.
Buhtoiarov IN, Lum H, Berke G, Paulnock DM, Sondel PM, Rakhmilevich AL. 2005. CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro. J Immunol 174:6013-22.
Neal ZC, Yang JC, Rakhmilevich AL, Buhtoiarov IN, Lum HD, Imboden M, Hank JA, Lode HN, Reisfeld RA, Gillies SD, Sondel PM. 2004. Enhanced activity of hu14.18-IL2 immunocytokine against murine NXS2 neuroblastoma when combined with interleukin 2 therapy. Clin Cancer Res 10:4839-47.