Thor Stein
| Years in MSTP | 1998-2006 |
| PhD | Neuroscience |
| Mentor | Jeffrey Johnson |
| Thesis | The Two Faces of the Amyloid Precursor Protein |
| Residency |
Pathology, Massachusetts General Hospital |
| Fellowship | Neuropathology, Massachusetts General Hospital |
Publications
Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkings MJ Jakel RJ, Johnson JA. 2005. Nrf2, a multi-organ protector? FASEB J 19:1061-6.
Li J, Stein TD, Johnson JA. 2004. Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics 18:261-72.
Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. 2004. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. J Neurosci 24:7707-17.
Stein TD, Fedynyshyn JP, Kalil RE. 2002. Circulating autoantibodies recognize and bind dying neurons following injury to the brain. J Neuropathol Exp Neurol 61:1100-8.
Diffee GM, Seversen EA, Stein TD, Johnson JA. 2003. Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles. Am J Physiol Heart Circ Physiol 284:H830-7.
Stein TD, Johnson JA. 2003. Genetic programming by the proteolytic fragments of the amyloid precursor protein: somewhere between confusion and clarity (review). Rev Neurosci 14:317-41.
Stein TD, Johnson JA. 2000. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci. 22:7380-8.