William Simonson
| Years in MSTP | 2002-2009 |
| PhD | Cellular and Molecular Biology |
| Mentor | Anna Huttenlocher |
| Thesis | The Roles of Talin1 and Calpain in T Cell Adhesion and Migration |
| Pathology | Pathology, University of Washington |
Publications
Wernimont SA, Simonson WT, Seroogy CM, Greer PA, Huttenlocher A. 2010. Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells. PLoS ONE:in press. PMC journal
Schartner JM, Simonson WT, Wernimont SA, Nettenstrom LM, Huttelocher A, Seroogy CM. 2009. Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during t cell antigen presenting cell interaction. J Biol Chem 284:34674-81. PMCID: 2787330.
Simonson WT, Markovina S, Grossman WJ, Lokuta MA, Doan AT, Seroogy CM, Huttenlocher A. 2009. Common variable immunodeficiency with regulatory T-cell deficiency treated with rapamycin (case report). Ann Allergy Asthma Immunol 102:170-1
Wang X, Chen X, Rodenkirch L, Simonson W, Wernimont S, Ndonye RM, Veerapen N, Gibson D, Howell AR, Besra GS, Painter GF, Huttenlocher A, Gumperz JE. 2008. Natural killer T-cell autoreactivity leads to a specialized activation state. Blood 112:4128-38. PMCID: 2570187
Wernimont SA, Cortesio CL, Simonson WT, Huttenlocher A. 2008. Adhesions ring: a structural comparison between podosomes and the immune synapse (review). Eur J Cell Biol 87:507-15. PMCID: 2570187
Simonson WT, Franco SJ, Huttenlocher A. 2006. Talin1 regulates TCR-mediated LFA-1 function. J Immunol 177:7707-14.
Franco SJ, Senetar MA, Simonson WT, Huttenlocher A, McCann RO. 2006. The conserved C-terminal I/LWEQ module targets Talin1 to focal adhesions. Cell Motil Cytoskeleton 63:563-81.
Su LT, Agapito MA, Li M, Simonson WT, Huttenlocher A, Habas R, Yue L, Runnels LW. 2006. TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem 281:11260-70.