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Home » ... » - Faculty » Faculty Pages » Cook, Mark E. |
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Cook, Mark E.
 Mark E. Cook, PhD
Professor
Research Area: Conjugated Linoleic Acid. Immunity. Inflammation. Cytokines. Cachexia. Lipids. Mode of action in chemicals, heavy metals, and nutrients in metabolism, immunity and disease.
Home Dept: Department of Animal Sciences
Affiliated Depts: Molecular and Environmental Toxicology; Department of Nutritional Sciences; Department of Bacteriology
Address
1064 Animal Sciences Bldg.
1675 Observatory Drive
Madison, WI 53706
608/262-7747 - Email
Research
Focus is on the nutritional regulation of immune function.
Companies
In the news July 13, 2008
2007 - Isomark, LLC This company is based on WARF patents developed by the founders for the early detection of infectious disease using biomarkers in breath. Scientist from UW-Madison founded Isomark, LLC including METC faculty Mark Cook, PhD and Warren Porter, Phd. Isomark's patented technology offers a unique non-invasive method for rapid detection of invasive infections. Goal is to assist healthcare providers achieve a critical need for earlier and more accurate diagnostic techniques.
2001 - AovaTechnologies Inc. - Company is based on antibodies for improving animal growth. Successor of company based on novel process of producing egg antibodies to prevent the collateral damage of immune responses, developed initially in the lab of Mark E. Cook, PhD in Animal Sciences. Aova Technologies is an agricultural biotechnology company and offers producers and feed nutritionist strategy in animal nutrition.
Patents
2006 - Composition containing gamete or embryo and animal white yolk and the use thereof
2002 - Method of using anti-phospholipase A2 antibodies to enhance growth or improve feed efficiency
2001 - Effect of L-Tryptophan Supplementation on Eosinophils and Eotaxin in Guinea Pigs
2000 - Eggs enriched with conjugated linoleic acid
2000 - Method for selectively altering body fat level, feed efficiently, or weight gain
2000 - Method of increasing fat firmness and improving meat quality in animals
1999 - Method for controlling body fat and/or body weight in animals and pharmaceutical compositions for...
1999 - Methods of treating animals to enhance natural killer lymphocyte function
1999 - Passive measurement of isotopes to monitor health
1998 - CCK antibodies used to improve feed efficiency
1998 - Compound to mimick a naturally occurring peptide's effect
1998 - Methods of treating animals to maintain or increase CD-4 and CD-8 cell populations
1998 - Methods of treating animals to maintain or enhance bone mineral content and compositions for use...
1998 - Use of CLA to reduce the incidence of valgus and varus leg deforomities in poultry ...
1996 - Methods of attenuating the allergic response in animals
1996 - Method for reducing body fat in animals
1995 - Method of increasing the efficiency of feed conversion in animals
1995 - Methods for preventing weight loss, reduction in weight gain, and anorexia due to immune stimulation
Publications- Li, G., D.E. Butz, and M.E. Cook. 2006. Selective conjugated fatty acids inhibit guinea pig platelet aggregation. Eu. J. Pharmacology 545:93-99
- Butz, D.E., G. Li, M.E. Cook 2006. t10,c12 conjugated linoleic acid induces compensatory growth after immune-challenge. J. Nutr Biochem. 17:735-741
- Li, G., B. Dong, D.E. Butz, Y Park, M.W. Paiza, and M.E. Cook. 2006 NF-kB independent inhibition of lipopolysaccharide-induced cyclooxygenase by a conjugated linoleic acid cognate, conjugated nonadecadienoic acid. Biochem. Biophy. Acta. 1761(9):969-972
- Li, G. D. Butz, D. Barnes, D. Bjorling, and M. E. Cook. 2005. 10t, 12c-conjugated linoleic acid inhibits lipopolysaccharide-induced cyclooxygenase protein expression in vitro and in vivo. J. Lipids Res. 46:2134-2142.
- Graves, E., A. Hitt, M.W. Pariza, M.E. Cook, and DE. O. McCarthy. 2004. Conjugated linoleic acid preserves gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. Res. Nurs. Health 28:48-55.
- Aydin, R. and M. E. Cook. 2005. The effect of dietary conjugated linoleic acid on egg yolk fatty acids and hatchability in japanese quail. Poultry Sci. 83:2016-2022.
- J. M. Storkson, Y. Park, M. E. Cook, and M. W. Pariza. 2004. Effects of trans-10, cis-12 conjugated linoleic acid (CLA) cognates on apolipoprotein B secretion in HepG2 cells. Nutr. Res. In press.
- Clark, W.D., E.L. Smith, K.A. Kim, J.R. Paul-Murphy, P. Muir, and M. E. Cook. 2005. Osteocyte apoptosis and osteoclast-like cell appearance in chicken radii following osteotomy. Intl. Bone. Min. submitted
- Clark, W. D., E. L. Smith, K. A. Linn, J. R. Paul-Murphy, and M. E. Cook. 2004. Using peripheral quantitative computed tomography to monitor bone healing following radial osteotomy in chicks. J. Avian Med. Surgery. In press.
- Cook, M.E. 2004. Antibodies:alternatives to antibiotics in improving growth and feed efficiency. Appl. J. Poultry Res. 13:106-119.
Check PubMed for other publications by Mark E. Cook
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