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Johnson, Eric A.


Eric A. Johnson, PhD
Professor

Research Area: Natural Toxins. Botulinum Neurotoxin. Clostridum Botulinum. Foodborne Pathogens. Genetics and biochemistry of botulinum toxin, the isolation and characterization of antimicrobial compounds from natural sources, and the biosynthesis of carotenoid pigments in yeasts found in unusual ecological niches.

Home Dept: Bacteriology, College of Agricultural and Life Sciences
Affiliated Depts: Molecular and Environmental Toxicology
Address
1925 Willow Drive
Madison, WI 53706-1114
Phone: 608/263-7944 - Email

Research
  • Interspecies transfer of the gene coding for botulinum toxins.
  • Regulation of expression of botulinum toxins.
  • li>Purification, stabilization, and characterization of botulinum toxins.
  • Development of botulinum toxin as a pharmaceutical.
  • Behavior and control of Clostridium botulinum in foods.
  • Assessment of the safety of new food processing procedures, e.g., modified atmosphere packaging, on safety from botulism.
  • Characterization and application in foods of naturally occurring antimicrobials, including lactoperoxidase, lactoferrin, monoglycerides, polyacetylenes, lysozyme, and other lytic enzymes.
  • Behavior and control of Listeria monocytogenes in foods.
  • Control of pathogens in reduced fat cheeses.

Publications
  • Chai Q, Arndt JW, Dong M, Tepp WH, Johnson EA, Chapman ER, Stevens RC. Structural basis of cell surface receptor recognition by botulinum neurotoxin B. Nature. 2006 Dec 13.
  • Hill KK, Smith TJ, Helma CH, Ticknor LO, Foley BT, Svensson RT, Brown JL, Johnson EA, Smith LA, Okinaka RT, Jackson PJ, Marks JD. Genetic Diversity Among Botulinum Neurotoxin Producing Clostridial Strains. J Bacteriol. 2006 Nov 17.
  • Butcher MK, Gilman J, Meszaros JF, Bjorsness D, Madison M, McDowall JM, Oser CS, Johnson EA, Harwell TS, Helgerson SD, Gohdes D. Improving access to quality diabetes education in a rural state: the Montana Quality Diabetes Education Initiative. Diabetes Educ. 2006 Nov-Dec;32(6):963-7.
  • Charron I, Johnson EA. The importance of fires and floods on tree ages along mountainous gravel-bed streams. Ecol Appl. 2006 Oct;16(5):1757-70.
  • Baird NA, Turnbull DW, Johnson EA. Induction of the Heat Shock Pathway during Hypoxia Requires Regulation of Heat Shock Factor by Hypoxia-inducible Factor-1. J Biol Chem. 2006 Dec 15;281(50):38675-81. Epub 2006 Oct 13.
  • Johnson EA, McCall JO, Partridge BS, Spalding EE, Palmer BB. Commission on journalism. J Am Coll Dent. 2006 Spring;73(1):14-7.
  • Xiang Y, Johnson EA, Zhang C, Huang G, Hayes RL, Wang KK, Svetlov SI. Generation of aberrant forms of DFF40 concurrent with caspase-3 activation during acute and chronic liver injury in rats. Biochem Biophys Res Commun. 2006 Nov 17;350(2):457-62. Epub 2006 Sep 22.
  • Arndt JW, Jacobson MJ, Abola EE, Forsyth CM, Tepp WH, Marks JD, Johnson EA, Stevens RC. A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4. J Mol Biol. 2006 Sep 29;362(4):733-42. Epub 2006 Jul 27.
  • Green D, Cushman M, Dermond N, Johnson EA, Castro C, Arnett D, Hill J, Manolio TA. Obtaining informed consent for genetic studies: The multiethnic study of atherosclerosis. Am J Epidemiol. 2006 Nov 1;164(9):845-51. Epub 2006 Aug 23.
  • Bakas T, Pressler SJ, Johnson EA, Nauser JA, Shaneyfelt T. Family caregiving in heart failure. Nurs Res. 2006 May-Jun;55(3):180-8.
    PMID: 16708042
Check PubMed for other publications by Eric A. Johnson
Date Last Updated: 04/28/2008