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Karasov, WIlliam H.

William H. Karasov, PhD
Professor

Research Area: Ecotoxicology. Wildlife. Amphibians. Bioavailability. Absorption. Plant Toxins. Physiological and ecological effects on wildlife of naturally occurring toxicants in their food and of environmental toxicants. Mechanisms of intestinal absorption and effects of toxicants on absorptive processes.

Home Dept: Wildlife Ecology, College of Agriculture and Life Sciences
Affiliated Depts: Molecular and Environmental Toxicology

Address
221 Russell Labs
1630 Linden Drive
Madison, WI 53706
Phone: 608/263-9319 - Email

Research
Nutritional Ecology--The relationships between the nutrient requirements of animals and the nutritional value of their food resources potentially affect diet selection, productivity, and survival. Professor Karasov and his students have performed laboratory and field studies on the nutritional ecology of several species of mammals and birds in order to explore the significance of nutrition in their ecology. This work includes studies of how antiherbivory chemicals in plants affect food selection, digestion, physiology, and population biology of herbivores.

Adaptation of digestion and intestinal nutrient absorption--Vertebrates differ considerably in the types of foods that they consume, but little is known of the physiological adaptations required for effective utilization of alternate food types. Professor Karasov and his students are studying the digestive physiology of animals with different dietary habits (such as carnivores, herbivores, omnivores, frugivores, and nectarivores) and also how intestinal nutrient absorption is regulated over the short-term (i.e., within a species) and
between species (i.e., over evolutionary time).

Energetics of animal foraging--All organisms need energy, and many activities of animals are centered around how to get, process it, and conserve it. Professor Karasov and his students are studying the energetics of free-living animals using doubly labeled water, micrometeorology, telemetry, and direct observation of behavior. They are documenting the physical, physiological, and behavioral factors which affect energy intake and expenditure, and the relationships between foraging behavior and reproductive success.

Wildlife Toxicology--Animals living in or feeding from the
Great Lakes are exposed to a number of pollutants, notably
polychlorinated biphenyls and dioxins. Professor Karasov and his
students are participating in studies to determine the level of
exposure of fish-eating birds and amphibians, and whether the
exposure causes physiological and behavioral disfunction and
effects on population biology.

Publications
  • McWhorter TJ, Bakken BH, Karasov WH, del Rio CM. Hummingbirds rely on both paracellular and carrier-mediated intestinal glucose absorption to fuel high metabolism. Biol Lett. 2006 Mar 22;2(1):131-4. PMID: 17148346
  • Fassbinder-Orth CA, Karasov WH. Effects of feed restriction and realimentation on digestive and immune function in the Leghorn chick. Poult Sci. 2006 Aug;85(8):1449-56.
  • Green AK, Haley SL, Barnes DM, Dearing MD, Karasov WH. Is alpha-pinene a substrate for permeability-glycoprotein in wood rats? J Chem Ecol. 2006 Jun;32(6):1197-211. Epub 2006 May 23.
  • Green AK, Haley SL, Barnes DM, Dearing MD, Karasov WH. Is alpha-Pinene a Substrate for Permeability-Glycoprotein in Wood Rats? J Chem Ecol. 2006 May 23
  • Chen TH, Gross JA, Karasov WH. Sublethal effects of lead on northern leopard frog (Rana pipiens) tadpoles. Environ Toxicol Chem. 2006 May;25(5):1383-9.
  • Chang MH, Karasov WH. Absorption and paracellular visualization of fluorescein, a hydrosoluble probe, in intact house sparrows (Passer domesticus). Zoology (Jena). 2004;107(2):121-33.
  • Chediack JG, Caviedes-Vidal E, Karasov WH. Electroaffinity in paracellular absorption of hydrophilic D-dipeptides by sparrow intestine. J Comp Physiol [B]. 2006 May;176(4):303-9. Epub 2005 Nov 30.
Check PubMed for other publications by William H. Karasov
Date Last Updated: 07/21/2008 webteam@med.wisc.edu