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Kaspar, Charles W.
 Charles W. Kaspar, PhD
Professor
Research Area: Acidophiles; microbial ecology; host–pathogen interactions.
Home Dept: Department of Bacteriology, College of Agricultural and Life Sciences
Affiliated Depts: Molecular and Environmental Toxicology
Address
3470 Microbial Sciences Bldg
1550 Linden Drive
Phone: 608/263-6936 - Email
ResearchMicrobial ecologyStress-response systems of Gram-negative bacteriaMolecular and physiological mechanisms of acid tolerance The research in my laboratory focuses on the isolation and characterization of acidophilic archaea, bacteria, and fungi. One area of emphasis is identifying and defining the function of proteins that protect or repair biomolecules, i.e. DNA. Studies with enterohemorrhagic E. coli O157:H7 are aimed at defining population dynamics and evolutionary processes affecting frequency and distribution. A variety of molecular and physiological approaches are used in these studies.
Publications- Jeong KC, Kang MY, Heimke C, Shere JA, Erol I, Kaspar CW. Isolation of Escherichia coli O157:H7 from the gall bladder of inoculated and naturally-infected cattle. Vet Microbiol. 2006 Aug 26
- Erol I, Jeong KC, Baumler DJ, Vykhodets B, Choi SH, Kaspar CW. H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage. BMC Microbiol. 2006 Aug 15;6:72.
- Baumler DJ, Hung KF, Bose JL, Vykhodets BM, Cheng CM, Jeong KC, Kaspar CW. Enhancement of acid tolerance in Zymomonas mobilis by a proton-buffering peptide. Appl Biochem Biotechnol. 2006 Jul;134(1):15-26
- Hung KF, Byrd JJ, Bose JL, Kaspar CW. Reduction of acid tolerance by tetracycline in Escherichia coli expressing tetA(C) is reversed by cations. Appl Environ Microbiol. 2006 Jun;72(6):4472-4.
- Jeong KC, Baumler DJ, Kaspar CW. dps expression in Escherichia coli O157:H7 requires an extended -10 region and is affected by the cAMP receptor protein. Biochim Biophys Acta. 2006 Jan-Feb;1759(1-2):51-9. Epub 2006 Mar 9. PMID: 16574257
Check PubMed for other publications by Charles W. Kaspar
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