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- Current Students
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Student Resources
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Student Publications
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Bae, JuYun
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Boehm, Bayli
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Boley, Patricia
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Bolterstein, Elyse
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Booth, Clarissa
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Brody, Matthew
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Bultman, JoAnna
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Desotelle, Josh
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Elmergreen, Tammy
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Hutchinson, John
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Irving, Amy
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Irving, Roy
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Johnson, Brian
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Johnson, Delinda
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Jung-Hynes, Brittney
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Kumar, Kartik
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Lee, Narae
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Lorch, Jeff
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Mehta, Vatsal
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Novick, Rachel
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Park, Heesoo
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Pham, Ly
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Rhoads, Keelia
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Rufer, Echoleah
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Sand, Jordan
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Schmit, Travis
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Shan, Weihua
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Shanle, Erin
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Shetty, Ameesha
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Syed, Deeba
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Tarapore, Rohinton
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Wiecinski, Paige
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Wong, Letitia
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Yang, Sarah
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Yu, Min
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Zhao, Yun
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Calkins, Marcus
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De Abrew, Nadira
Nadira De Abrew
PhD Candidate - Graduated Fall 2007
Native of Sri Lanka
Lab of B. Lynn Allen-Hoffmann, PhD
Contact Information
Email: Nadira DeAbrew
Undergraduate Work
Research as of 2004
My thesis project is now focused on the aryl hydrocarbon receptor nuclear translocator (ARNT). This protein acts as a dimerization pairer for many members of the basic helix-loop-helix-Per/ARNT/Sim (bHLH-PAS) family of transcription factors. Members of this family are involved in regulation of gene expression in response to environmental stimuli such as hypoxia (HIF-1a/ARNT) and xenobiotics (AhR/ARNT). A recent report demonstrates that skin-specific knockout of ARNT in mice causes compromised barrier function in skin resulting in neonatal lethality within 24 hours. These findings support the notion that ARNT plays a critical role in the late stages of mouse skin differentiation prior to production of fur.
Posters
ARNT1 Has A Role in the Innate Immune Response In Human Keratinocytes. K. N. DeAbrew1, A. L. Gibson,2 , and B. Allen-Hoffmann1,2, 1Molecular and Environmental Toxicology, University of Wisconsin, Madison, WI and 2Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI
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