Undergraduate education

Cornell University - BS (2010)

Years in MSTP



Epidemiology, 2017


Ajay Sethi, PhD, MHS

Nasia Safdar, MD, MS

Oguzhan Alagoz, PhD

Thesis title

Patient- and hospital-centered interventions to reduce the incidence of Clostridium difficile infection: An agent-based modeling approach to evaluate clinical and cost effectiveness


Internal Medicine, University of Michigan, 2019-

Postdoctoral fellowship

Pulmonary and Critical Care, 2021-2015

Current position

Resident, Department of Internal Medicine, University of Michigan School of Medicine

Undergraduate and/or masters publications

Ching YH, Munroe RJ, Moran JL, Barker AK, Mauceli E, Fennell T, Dipalma F, Lindblad-Toh K, Abcunas LM, Gilmour JF, Harris TP, Kloet SL, Luo Y, McElwee JL, Mu W, Park HK, Rogal DL, Schimenti KJ, Shen L, Shindo M, Shou JY, Stenson EK, Stover PJ, Schimenti JC. High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. BMC Genet. 2010 Nov 30;11:106. PMID: 21118569; PMCID: PMC3009607. 

Mu W, Munroe RJ, Barker AK, Schimenti JC. PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance. Dev Biol. 2010 Nov 15;347(2):279-88. PMID: 20813103; PMCID: PMC2957520.

PhD Publications

De Wolfe TJ, Eggers S, Barker AK, Kates AE, Dill-McFarland KA, Suen G, Safdar N. Oral probiotic combination of Lactobacillus and Bifidobacterium alters the gastrointestinal microbiota during antibiotic treatment for Clostridium difficile infection. PLoS One. 2018;13(9):e0204253. Collection 2018. PMID: 30265691; PMCID: PMC6161886.

Abad CL, Barker AK, Safdar N. A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associated C. difficile and multidrug-resistant organisms. Infect Control Hosp Epidemiol. 2020 Jun;41(6):691-709. PMID: 32216852.

Barker AK, Scaria E, Alagoz O, Sethi AK, Safdar N. Reducing C. difficile in children: An agent-based modeling approach to evaluate intervention effectiveness. Infect Control Hosp Epidemiol. 2020 May;41(5):522-530. PMID: 32052722.

Barker AK, Moreno MA. Effects of Recreational Marijuana Legalization on College Students: A Longitudinal Study of Attitudes, Intentions, and Use Behaviors. J Adolesc Health. 2020 May 8. pii: S1054-139X(20)30155-5. [Epub ahead of print] PMID: 32402801.

Barker AK, Cowley ES, McKinley L, Wright MO, Safdar N. An in-room observation study of hand hygiene and contact precaution compliance for Clostridioides difficile patients. Am J Infect Control. 2019 Oct;47(10):1273-1276. PMID: 31060870; PMCID PMC6913874.

Eggers S, Barker AK, Valentine S, Hess T, Duster M, Safdar N. Effect of Lactobacillus rhamnosus HN001 on carriage of Staphylococcus aureus: results of the impact of probiotics for reducing infections in veterans (IMPROVE) study. BMC Infect Dis. 2018 Mar 14;18(1):129. PMID:29540160; PMCID: PMC5853063.

Barker AK, Codella J, Ewers T, Dundon A, Alagoz O, Safdar N. Changes to physician and nurse time burdens when caring for patients under contact precautions. Am J Infect Control. 2017 May 1;45(5):542-543. Epub 2017 Mar 13. PMID: 28302435; PMCID: PMC6215360.

Barker AK, Brown K, Siraj D, Ahsan M, Sengupta S, Safdar N. Barriers and facilitators to infection control at a hospital in northern India: a qualitative study. Antimicrob Resist Infect Control. 2017 Apr 8;6:35. eCollection 2017. PMID: 28405312; PMCID: PMC5385016.

Barker AK, Brown K, Ahsan M, Sengupta S, Safdar N. Social determinants of antibiotic misuse: a qualitative study of community members in Haryana, India. BMC Public Health. 2017 Apr 19;17(1):333. PMID: 28420365; PMCID: PMC5395834.

Barker AK, Ngam C, Musuuza JS, Vaughn VM, Safdar N. Reducing Clostridium difficile in the Inpatient Setting: A Systematic Review of the Adherence to and Effectiveness of C. difficile Prevention Bundles. Infect Control Hosp Epidemiol. 2017 Jun;38(6):639-650. PMID: 28343455; PMCID: PMC5654380.

Barker AK, Brown K, Ahsan M, Sengupta S, Safdar N. What drives inappropriate antibiotic dispensing? A mixed-methods study of pharmacy employee perspectives in Haryana, India. BMJ Open. 2017 Mar 2;7(3):e013190. PMID: 28255093; PMCID: PMC5353334.

Cannon CM, Musuuza JS, Barker AK, Duster M, Juckett MB, Pop-Vicas AE, Safdar N. Risk of Clostridium difficile Infection in Hematology-Oncology Patients Colonized With Toxigenic C. difficile. Infect Control Hosp Epidemiol. 2017 Jun;38(6):718-720. PMID: 28397624; PMCID: PMC5531265.

Eggers S, Barker A, Valentine S, Hess T, Duster M, Safdar N. Impact of Probiotics for Reducing Infections in Veterans (IMPROVE): Study protocol for a double-blind, randomized controlled trial to reduce carriage of Staphylococcus aureus. Contemp Clin Trials. 2017 Jan;52:39-45. PMID: 27836508; PMCID: PMC5670736.

Musuuza JS, Barker A, Ngam C, Vellardita L, Safdar N. Assessment of Fidelity in Interventions to Improve Hand Hygiene of Healthcare Workers: A Systematic Review. Infect Control Hosp Epidemiol. 2016 May;37(5):567-75. PMID: 26861117; PMC4853201.

Barker A, Sethi A, Shulkin E, Caniza R, Zerbel S, Safdar N. Patients' hand hygiene at home predicts their hand hygiene practices in the hospital. Infect Control Hosp Epidemiol. 2014 May;35(5):585-8. Epub 2014 Mar 18. PMID: 24709731; PMCID PMC4148899.

Barker A, Duster M, Valentine S, Archbald-Pannone L, Guerrant R, Safdar N. Probiotics for Clostridium difficile infection in adults (PICO): Study protocol for a double-blind, randomized controlled trial. Contemp Clin Trials. 2015 Sep;44:26-32. Epub 2015 Jul 22. PMID: 26210512; PMCID: PMC4723294.

Arriola V, Tischendorf J, Musuuza J, Barker A, Rozelle JW, Safdar N. Assessing the Risk of Hospital-Acquired Clostridium Difficile Infection With Proton Pump Inhibitor Use: A Meta-Analysis. Infect Control Hosp Epidemiol. 2016 Dec;37(12):1408-1417. PMID: 27677811; PMCID: PMC5657489.

Barker AK, Van Galen A, Sethi AK, Shirley D, Safdar N. Tobacco use as a screener for Clostridium difficile infection outcomes. J Hosp Infect. 2018 Jan;98(1):36-39. PMID: 28655511; PMCID: PMC5743584.

Seibert G, Ewers T, Barker AK, Slavick A, Wright MO, Stevens L, Safdar N. What do visitors know and how do they feel about contact precautions? Am J Infect Control. 2018 Jan;46(1):115-117. PMID: 28732742; PMCID: PMC6245601.

Barker AK, Krasity B, Musuuza J, Safdar N. Screening for Asymptomatic Clostridium difficile Among Bone Marrow Transplant Patients: A Mixed-Methods Study of Intervention Effectiveness and Feasibility. Infect Control Hosp Epidemiol. 2018 Feb;39(2):177-185. PMID: 29366434; PMCID: PMC6239859.

Barker AK, Alagoz O, Safdar N. Interventions to reduce the incidence of hospital-onset Clostridium difficile infection: An agent-based modeling approach to evaluate clinical effectiveness in adult acute care hospitals. Clin Infect Dis. 2018 Apr 3;66(8):1192-1203. PMID: 29112710; PMCID: PMC5888988.

Kalluru S, Eggers S, Barker A, Shirley D, Sethi AK, Sengupta S, Yeptho K, Safdar N. Risk factors for infection with multidrug-resistant organisms in Haryana, India. Am J Infect Control. 2018 Mar;46(3):341-345. PMID: 29102426; PMCID: PMC6055232.

Barker AK, Duster M, Valentine S, Hess T, Archbald-Pannone L, Guerrant R, Safdar N. A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO). J Antimicrob Chemother. 2017 Nov; 72(11):3177-3180. PMID: 28961980; PMCID: PMC5890711.

Barker AK, Zellmer C, Tischendorf J, Duster M, Valentine S, Wright MO, Safdar N. On the hands of patients with Clostridium difficile: A study of spore prevalence and the effect of hand hygiene on C difficile removal. Am J Infect Control. 2017 Oct 1;45(10):1154-1156. PMID: 28964347; PMCID: PMC5731647.

Mitchell KF, Barker AK, Abad CL, Safdar N. Infection control at an urban hospital in Manila, Philippines: a systems engineering assessment of barriers and facilitators. Antimicrob Resist Infect Control. 2017 Sep 2;6:90. PMID: 28883912; PMCID: PMC5581421.