Undergraduate education

University of New Mexico, BS, 2002

Years in MSTP

2003-2013

PhD

Physiology, 2011

Mentor

Richard Moss, PhD

Thesis title

Function of cardiac myosin-binding protein C in cardiac health and disease

Residency

Pathology, Yale University, 2014-

Current position

Resident, Department of Pathology, Yale University, School of Medicine

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Undergraduate and/or masters publications

Omdahl JL, Bobrovnikova EV, Annalora A, Chen P, Serda R. Expression, structure-function, and molecular modeling of vitamin D P450s. J Cell Biochem. 2003 Feb 1;88(2):356-62. PMID: 12520537.

PhD publications

Chen PP, Patel JR, Powers PA, Fitzsimons DP, Moss RL. Dissociation of structural and functional phenotypes in cardiac Myosin-binding protein C conditional knockout mice. Circulation. 2012 Sep 4;126(10):1194-205. PMCID: PMID: 22829020; PMCID: PMC3466088.

Colson BA, Patel JR, Chen PP, Bekyarova T, Abdalla MI, Tong CW, Fitzsimons DP, Irving TC, Moss RL. Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium. J Mol Cell Cardiol. 2012 Nov;53(5):609-16. PMID: 22850286; PMCID: PMC3472100.

Chen PP, Patel JR, Rybakova IN, Walker JW, Moss RL. Protein kinase A-induced myofilament desensitization to Ca(2+) as a result of phosphorylation of cardiac myosin-binding protein C. J Gen Physiol. 2010 Dec;136(6):615-27. PMID: 21115695; PMCID: PMC2995154.

Stelzer JE, Norman HS, Chen PP, Patel JR, Moss RL. Transmural variation in myosin heavy chain isoform expression modulates the timing of myocardial force generation in porcine left ventricle. J Physiol. 2008 Nov 1;586(Pt 21):5203-14. PMID: 18787035; PMCID: PMC2652156.