Undergraduate education

University of Chicago, BA, 1990

Years in MSTP



Human oncology, 1997


Paul Sondel, MD, PhD

Thesis title

Functional Responses and Receptor Usage of Human Lymphocytes in Response to Interlukin-2 and Interlukin-15


Pediatrics, Children's Hospital of Boston


Hematology-oncology, Children's Hospital of Boston

Current position

Assistant professor, Department of Pediatrics, Biological Sciences Division, School of Medicine, University of Chicago

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PhD publications

Monson NL, Fenske TJ, Wei S, Okragly AJ, de Jong JL, Haak-Frendscho M, O'Shea J, Djeu J, Sondel PM. A p74 common gamma receptor chain isoform facilitates IL-2 and IL-15 responses by the myelomonocytic cell line Tf-1beta2. J Leukoc Biol. 2001 Mar;69(3):419-25. PMID: 11261789.

De Jong JL, Farner NL, Sondel PM. Distinctions in lymphocyte responses to IL-2 and IL-15 reflect differential ligand binding interactions with the IL-2Rbeta chain and suggest differential roles for the IL-2Ralpha and IL-15Ralpha subunits. Cytokine. 1998 Dec;10(12):920-30. PMID: 10049515.

De Jong JL, Farner NL, Javorsky BR, Lindstrom MJ, Hank JA, Sondel PM. Differential quantitative effects of interleukin (IL)-2 and IL-15 on cytotoxic activity and proliferation by lymphocytes from patients receiving in vivo IL-2 therapy. Clin Cancer Res. 1998 May;4(5):1287-96. PMID: 9607589.

Farner NL, Gan J, de Jong JL, Leary TP, Fenske TS, Buckley P, Dunlap S, Sondel PM. Alteration of the CD34+ Tf-1 beta cell line profile in response to long-term exposure to IL-15. Cytokine. 1997 May;9(5):316-27. PMID: 9195130.

De Jong JL, Farner NL, Widmer MB, Giri JG, Sondel PM. Interaction of IL-15 with the shared IL-2 receptor beta and gamma c subunits. The IL-15/beta/gamma c receptor-ligand complex is less stable than the IL-2/beta/gamma c receptor-ligand complex. J Immunol. 1996 Feb 15;156(4):1339-48. PMID: 8568232.

Kaur I, de Jong J, Schell K, Hank J, Fisch P, Sondel PM. Human peripheral gamma delta T cells are stimulated by Daudi Burkitt's lymphoma and not by any other Burkitt's lymphoma tested. Cell Immunol. 1994 Jun;156(1):54-61. PMID: 8200042.