Undergraduate education

St. Olaf College, BA, 1998

Years in MSTP

1999-2008

PhD

Neuroscience, 2006

Mentor

Jeffrey Johnson, PhD

Thesis title

The Antioxidant Response Element and Dopaminergic Toxicity

Residency

Psychiatry, Duke University, 2008-2012

Current position

Assistant professor, Department of Psychiatry and Behavioral Sciences, Duke University, School of Medicine

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PhD publications

Johnson JA, Johnson DA, Kraft AD, Calkins MJ, Jakel RJ, Vargas MR, Chen PC. The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. Ann N Y Acad Sci. 2008 Dec;1147:61-9. PMID: 19076431; PMCID: PMC2605641.

Jakel RJ, Townsend JA, Kraft AD, Johnson JA. Nrf2-mediated protection against 6-hydroxydopamine. Brain Res. 2007 May 4;1144:192-201. PMID: 17336276; PMCID: PMC2062573.

Jakel RJ, Kern JT, Johnson DA, Johnson JA. Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. Toxicol Sci. 2005 Sep;87(1):176-86. PMID: 15976186.

Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, Jakel RJ, Johnson JA. Nrf2, a multi-organ protector? FASEB J. 2005 Jul;19(9):1061-6. PMID: 15985529.

Calkins MJ, Jakel RJ, Johnson DA, Chan K, Kan YW, Johnson JA. Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Proc Natl Acad Sci USA. 2005 Jan 4;102(1):244-9. PMID: 15611470; PMCID: PMC538748.

McBride JL, Behrstock SP, Chen EY, Jakel RJ, Siegel I, Svendsen CN, Kordower JH. Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. J Comp Neurol. 2004 Jul 19;475(2):211-9. PMID: 15211462.

Jakel RJ, Schneider BL, Svendsen CN. Using human neural stem cells to model neurological disease. Nat Rev Genet. 2004 Feb;5(2):136-44. PMID: 14735124.

Jakel RJ, Maragos WF. Neuronal cell death in Huntington's disease: a potential role for dopamine. Trends Neurosci. 2000 Jun;23(6):239-45. PMID: 10838590.