Undergraduate education

Massachusetts Institute of Technology, BS (1999)

Years in MSTP

2004-2010

PhD

Biochemistry, 2006

Mentor

Aseem Ansari, PhD

Thesis title

Chemical genomics analysis of TFIIH kinase function in saccharomyces cerevisiae

Residency

Internal medicine, Baylor College of Medicine, 2010-2013

Fellowship

Cardiology, Yale University, 2013-2016

Current position

Cardiologist, Windham Hospital, Hartford HealthCare Medical Group, Hartford, Connecticut

Undergraduate or masters publications

Ren B, Robert F, Wyrick JJ, Aparicio O, Jennings EG, Simon I, Zeitlinger J, Schreiber J, Hannett N, Kanin E, Volkert TL, Wilson CJ, Bell SP, Young RA. Genome-wide location and function of DNA binding proteins. Science. 2000 Dec 22;290(5500):2306-9. PMID: 11125145.

Causton HC, Ren B, Koh SS, Harbison CT, Kanin E, Jennings EG, Lee TI, True HL, Lander ES, Young RA. Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell. 2001 Feb;12(2):323-37. PMID:11179418; PMCID: PMC30946.

PhD publications

Davis SE, Mooney RA, Kanin EI, Grass J, Landick R, Ansari AZ. Mapping E. coli RNA polymerase and associated transcription factors and identifying promoters genome-wide. Methods Enzymol. 2011;498:449-71. PMID: 21601690.

Mareedu RK, Modhia FM, Kanin EI, Linneman JG, Kitchner T, McCarty CA, Krauss RM, Wilke RA. Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity. Prev Cardiol. 2009 Spring;12(2):88-94. PMID: 19476582; PMCID: PMC3773543.

Kanin EI, Kipp RT, Kung C, Slattery M, Viale A, Hahn S, Shokat KM, Ansari AZ. Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis. Proc Natl Acad Sci USA. 2007 Apr 3;104(14):5812-7. PMID: 17392431; PMCID: PMC1851574.

Raffaelle M, Kanin EI, Vogt J, Burgess RR, Ansari AZ. Holoenzyme switching and stochastic release of sigma factors from RNA polymerase in vivo. Mol Cell. 2005 Nov 11;20(3):357-66. PMID: 16285918.

Herring CD, Raffaelle M, Allen TE, Kanin EI, Landick R, Ansari AZ, Palsson BØ. Immobilization of Escherichia coli RNA polymerase and location of binding sites by use of chromatin immunoprecipitation and microarrays. J Bacteriol. 2005 Sep;187(17):6166-74. PMID: 16109958; PMCID: PMC1196165.