Kim Krautkramer
Undergraduate education
University of Wisconsin-Madison - BS (2010)
Years in MSTP
2011-2019
PhD program
Biochemistry, 2017
Mentor
Thesis title
Mice, microbiota, and hibernators: Interactions between environment, the gut microbiota, and the host epigenome
Postdoctoral fellowship
Gothenburg University, Sweden, 2019-2021
Current position
Postdoctoral fellow, Gothenburg University
Undergraduate and/or masters publications
Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol. 2010 Sep;24(9):1822-34. PMID: 20660304; PMCID: PMC2940473.
Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta cell line. Am J Physiol Endocrinol Metab. 2013 Sep;305(5):E600-10. PMID: 23860123; PMCID: PMC3761170.
PhD publications
Kasahara K, Krautkramer KA, Org E, Romano KA, Kerby RL, Vivas EI, Mehrabian M, Denu JM, Bäckhed F, Lusis AJ, Rey FE. Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model. Nat Microbiol. 2018 Dec;3(12):1461-1471. PMID: 30397344; PMCID: PMC6280189.
Su Z, Wang F, Lee JH, Stephens KE, Papazyan R, Voronina E, Krautkramer KA, Raman A, Thorpe JJ, Boersma MD, Kuznetsov VI, Miller MD, Taverna SD, Phillips GN Jr, Denu JM. Reader domain specificity and lysine demethylase-4 family function. Nat Commun. 2016 Nov 14;7:13387. PMID: 27841353; PMCID: PMC5114558.
Krautkramer KA, Kreznar JH, Romano KA, Vivas EI, Barrett-Wilt GA, Rabaglia ME, Keller MP, Attie AD, Rey FE, Denu JM. Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues. Mol Cell. 2016 Dec 1;64(5):982-992. PMID: 27889451; PMCID: PMC5227652.
Yu W, Denu RA, Krautkramer KA, Grindle KM, Yang DT, Asimakopoulos F, Hematti P, Denu JM. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies. J Biol Chem. 2016 Feb 12;291(7):3258-79. PMID: 26631723; PMCID: PMC4751373.
Fan J, Krautkramer KA, Feldman JL, Denu JM. Metabolic regulation of histone post-translational modifications. ACS Chem Biol. 2015 Jan 16;10(1):95-108. PMID: 25562692; PMCID: 4407823.
Krautkramer KA, Reiter L, Denu JM, Dowell JA. Quantification of SAHA-Dependent Changes in Histone Modifications Using Data-Independent Acquisition Mass Spectrometry. J Proteome Res. 2015 Aug 7;14(8):3252-62. PMID: 26120868. PMCID: PMC4564294.
Rensvold JW, Krautkramer KA, Dowell JA, Denu JM, Pagliarini DJ. Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis. J Biol Chem. 2016 Sep 30;291(40):20827-20837. PMID: 27497435; PMCID: PMC5076495.
Krautkramer KA, Rey FE, Denu JM. Chemical signaling between gut microbiota and host chromatin: What is your gut really saying? J Biol Chem. 2017 May 26;292(21):8582-8593. Review. PMID: 28389558; PMCID: PMC5448088.
Krautkramer KA, Dhillon RS, Denu JM, Carey HV. Metabolic programming of the epigenome: host and gut microbial metabolite interactions with host chromatin. Transl Res. 2017 Nov;189:30-50. Review. PMID: 28919341; PMCID: PMC5659875.
Zhang XS, Li J, Krautkramer KA, Badri M, Battaglia T, Borbet TC, Koh H, Ng S, Sibley RA, Li Y, Pathmasiri W, Jindal S, Shields-Cutler RR, Hillmann B, Al-Ghalith GA, Ruiz VE, Livanos A, Wout A, Nagalingam N, Rogers AB, Sumner SJ,
Knights D, Denu JM, Li H, Ruggles KV, Bonneau R, Williamson AR, Rauch M, Blaser MJ. Antibiotic-induced acceleration of type 1 diabetes alters maturation of innate intestinal immunity. Elife. 2018 Jul 25;7. pii: e37816. PMID: 30039798; PMCID: PMC6085123.