Undergraduate education

Kenyon College, BA, 2004

Years in MSTP

2004-2012

PhD

Cellular and molecular biology, 2010

Mentor

Alan Attie, PhD

Thesis title

FoxM1 and Cholecystokinin control beta-cell mass regulation during obesity and diabetes

Residency

Ophthalmology, University of Wisconsin-Madison, 2012-2016

Fellowship

Ophthalmology, Surgical Retina Fellowship, Cleveland Clinic Foundation, 2016-2018

Current position

Fellow, Department of Ophthalmology, Cleveland Clinic Foundation

Undergraduate or masters publications

Lavine JA, Rowatt AJ, Klimova T, Whitington AJ, Dengler E, Beck C, Powell WH. Aryl hydrocarbon receptors in the frog Xenopus laevis: two AhR1 paralogs exhibit low affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci. 2005 Nov;88(1):60-72. PMID: 15958654; PMCID: PMC1255970.

PhD publications

Lavine JA, Attie AD. Gastrointestinal hormones and the regulation of β-cell mass. Ann N Y Acad Sci. 2010 Nov;1212:41-58. PMID: 21039588.

Davis DB, Lavine JA, Suhonen JI, Krautkramer KA, Rabaglia ME, Sperger JM, Fernandez LA, Yandell BS, Keller MP, Wang IM, Schadt EE, Attie AD. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol. 2010 Sep;24(9):1822-34. PMID: 20660304; PMCID: PMC2940473.

Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology. 2010 Aug;151(8):3577-88. PMID: 20534724;PMCID: PMC2940525.

Lavine JA, Raess PW, Davis DB, Rabaglia ME, Presley BK, Keller MP, Beinfeld MC, Kopin AS, Newgard CB, Attie AD. Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note. Mol Endocrinol. 2010 Feb;24(2):464-7. PMID: 20081104; PMCID: PMC2817600.

Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 beta cell line. Am J Physiol Endocrinol Metab. 2013 Sep;305(5):E600-10. PMID: 23860123; PMCID: PMC3761170.