Undergraduate education

Kenyon College, BA, 2004

Years in MSTP

2004-2013

PhD

Molecular and cellular pharmacology, 2011

Mentor

Deane Mosher, MD

Thesis title

The role of beta-strand addition in fibronectin function

Residency

Pediatrics, University of California-San Francisco, 2013-2016

Fellowship

Pediatrics-Hematology/Oncology, University of Pittsburgh, School of Medicine, 2016-

Current position

Fellow, Department of Pediatrics-Hematology/Oncology, University of Pittsburgh, School of Medicine

Undergraduate and/or masters publications

Maurer LM, Yohannes E, Bondurant SS, Radmacher M, Slonczewski JL. pH regulates genes for flagellar motility, catabolism, and oxidative stress in Escherichia coli K-12. J Bacteriol. 2005 Jan;187(1):304-19. PMID: 15601715; PMCID: PMC538838.

Abram CL, Seals DF, Pass I, Salinsky D, Maurer L, Roth TM, Courtneidge SA. The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells. J Biol Chem. 2003 May 9;278(19):16844-51. PMID: 12615925.

Kirkpatrick C, Maurer LM, Oyelakin NE, Yoncheva YN, Maurer R, Slonczewski JL. Acetate and formate stress: opposite responses in the proteome of Escherichia coli. J Bacteriol. 2001 Nov;183(21):6466-77. PMID: 11591692; PMCID: PMC100143.

PhD publications

Maurer LM, Ma W, Eickstaedt NL, Johnson IA, Tomasini-Johansson BR, Annis DS, Mosher DF. Ligation of the fibrin-binding domain by β-strand addition is sufficient for expansion of soluble fibronectin. J Biol Chem. 2012 Apr 13;287(16):13303-12. PMID: 22351755; PMCID: PMC3339936.

Maurer LM, Annis DS, Mosher DF. IGD motifs, which are required for migration stimulatory activity of fibronectin type I modules, do not mediate binding in matrix assembly. PLoS One. 2012;7(2):e30615. PMID: 22355321; PMCID: PMC3280255.

Maurer LM, Tomasini-Johansson BR, Ma W, Annis DS, Eickstaedt NL, Ensenberger MG, Satyshur KA, Mosher DF. Extended binding site on fibronectin for the functional upstream domain of protein F1 of Streptococcus pyogenes. J Biol Chem. 2010 Dec 24;285(52):41087-99. PMID: 20947497; PMCID: PMC3003407.

Xu J, Maurer LM, Hoffmann BR, Annis DS, Mosher DF. iso-DGR sequences do not mediate binding of fibronectin N-terminal modules to adherent fibronectin-null fibroblasts. J Biol Chem. 2010 Mar 19;285(12):8563-71. PMID: 20097751; PMCID: PMC2838278.

Maurer LM, Tomasini-Johansson BR, Mosher DF. Emerging roles of fibronectin in thrombosis. Thromb Res. 2010 Apr;125(4):287-91. PMID: 20116835; PMCID: PMC2877496.

Mosher DF, Maurer LM, Carlson CB. Secreted thrombospondin-1 controls platelet sensitivity to NO. Blood. 2008 Jan 15; 111(2):473-74.

Moussavi-Harami SF, Annis DS, Ma W, Berry SM, Coughlin EE, Strotman LN, Maurer LM, Westphall MS, Coon JJ, Mosher DF, Beebe DJ. Characterization of Molecules Binding to the 70K N-Terminal Region of Fibronectin by IFAST Purification Coupled with Mass Spectrometry. J Proteome Res. 2013 Jul 5;12(7):3393-404. PMID: 23750785; PMCID: PMC3832424.

Harris G, Ma W, Maurer LM, Potts JR, Mosher DF. Borrelia burgdorferi protein BBK32 binds to soluble fibronectin via the N-terminal 70 kDa region, causing fibronectin to undergo conformational extension. J Biol Chem. 2014 Aug 8;289(32):22490-22499. Epub 2014 Jun 24. PMID: 24962582; PMCID: PMC4139255.

Maurer LM, Ma W, Mosher DF. Dynamic structure of plasma fibronectin. Crit Rev Biochem Mol Biol. 2015 Jul-Aug;51(4):213-27. PMID: 27185500; PMCID: PMC4929849.