Undergraduate education

Lafayette College, BS, 1993

Years in MSTP

1995-2000

PhD

Biochemistry, 1997

Mentor

W. Wallace Cleland, PhD

Thesis title

Insight Into the Mechanism of Enzymatic Phosphoryl Transfer Through Investigation of Transition State Structures

Residency

Rehabilitation medicine, Northwestern University, 2001-2004

Current position

Associate professor, Department of Physical Medicine and Rehabilitation, University of Pittsburgh, School of Medicine

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PhD publications

Gerratana B, Sowa GA, Cleland WW. Characterization of the transition-state structures and mechanisms for the isomerization and cleavage reactions uridine 3'-m-Nitrobenzyl phosphate. J Am Chem Soc. 2000 Dec 27; 122(51):12615-12621.

Poyner RR, Laughlin LT, Sowa GA, Reed GH. Toward identification of acid/base catalysts in the active site of enolase: comparison of the properties of K345A, E168Q, and E211Q variants. Biochemistry. 1996 Feb 6;35(5):1692-9. PMID: 8634301.

Hengge AC, Sowa GA, Wu L, Zhang ZY. Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction. Biochemistry. 1995 Oct 31;34(43):13982-7. PMID: 7577995.

Sowa GA, Hengge AC, Cleland WW. O-18 isotope effects support a concerted mechanism for ribonuclease A. Journal of the American Chemical Society. 1997 Mar;119(9):2319-2320.