Undergraduate education

University of Wisconsin-Madison, BS, 1998

Years in MSTP



Neuroscience, 2004


Jeffrey Johnson, PhD

Thesis title

The Two Faces of the Amyloid Precursor Protein


Pathology, Massachusetts General Hospital, 2007-2010


Neuropathology, Massachusetts General Hospital, 2010-2011

Current position

Assistant professor, Department of Pathology and Laboratory Medicine, Boston University

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Undergraduate and/or masters publications

Stein TD, DeJesus OT. Effect of 6-fluoro-m-tyrosine on dopamine release and metabolism in rat striatum using in vivo microdialysis. Brain Res. 2000 Nov 24;884(1--2):192-5. PMID: 11082501.

Stein T, Moritz C, Quigley M, Cordes D, Haughton V, Meyerand E. Functional connectivity in the thalamus and hippocampus studied with functional MR imaging. AJNR Am J Neuroradiol. 2000 Sep;21(8):1397-401. PMID: 11003270.

PhD publications

Lee JM, Li J, Johnson DA, Stein TD, Kraft AD, Calkins MJ, Jakel RJ, Johnson JA. Nrf2, a multi-organ protector? FASEB J. 2005 Jul;19(9):1061-6. PMID: 15985529.

Stein TD, Anders NJ, DeCarli C, Chan SL, Mattson MP, Johnson JA. Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis. J Neurosci. 2004 Sep 1;24(35):7707-17. PMID: 15342738.

Li J, Stein TD, Johnson JA. Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics. 2004 Aug 11;18(3):261-72. PMID: 15173550.

Stein TD, Johnson JA. Genetic programming by the proteolytic fragments of the amyloid precursor protein: somewhere between confusion and clarity. Rev Neurosci. 2003;14(4):317-41. PMID: 14640319.

Stein TD, Fedynyshyn JP, Kalil RE. Circulating autoantibodies recognize and bind dying neurons following injury to the brain. J Neuropathol Exp Neurol. 2002 Dec;61(12):1100-8. PMID: 12484573.

Diffee GM, Seversen EA, Stein TD, Johnson JA. Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles. Am J Physiol Heart Circ Physiol. 2003 Mar;284(3):H830-7. PMID: 12424097.

Stein TD, Johnson JA. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci. 2002 Sep 1;22(17):7380-8. PMID: 12196559.