Profile of Jack Hunt

Undergraduate education

Stanford University - BA (2009)

Years in MSTP

2013-

PhD program

Cellular and Molecular Biology

Mentor

Xinyu Zhao, PhD

Research interest

I am interested in using human and animal neural stem cell models to understand the genetic and molecular causes of neurodevelopmental diseases such as Fragile X Syndrome and Rett Syndrome. In my research I hope to identify the downstream targets of disease-causing gene products in order to guide the development of early interventions and therapeutics.

Undergraduate and/or masters publications

Atkin G, Moore S, Lu Y, Nelson RF, Tipper N, Rajpal G, Hunt J, Tennant W, Hell JW, Murphy GG, Paulson H. Loss of F-box Only Protein 2 (Fbxo2) Disrupts Levels and Localization of Select NMDA Receptor Subunits, and Promotes Aberrant Synaptic Connectivity. J Neurosci. 2015 Apr 15;35(15):6165-78. PMID: 25878288; PMCID: PMC4397610.

Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L. Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med. 2012 Jul 2;209(7):1325-34. PMID: 22734047; PMCID: PMC3405500.

Olsen RK, Nichols EA, Chen J, Hunt JF, Glover GH, Gabrieli JD, Wagner AD. Performance-related sustained and anticipatory activity in human medial temporal lobe during delayed match-to-sample. J Neurosci. 2009 Sep 23;29(38):11880-90. PMID: 19776274; PMCID: PMC2775810.

Atkin G, Hunt J, Minakawa E, Sharkey L, Tipper N, Tennant W, Paulson HL. F-box only protein 2 (Fbxo2) regulates amyloid precursor protein levels and processing. J Biol Chem. 2014 Mar 7;289(10):7038-48. PMID: 24469452; PMCID: PMC3945364.