Anna Huttenlocher, MD

Anna Huttenlocher
Director

Dr. Anna Huttenlocher became director of the UW Medical Scientist Training Program (MSTP) in 2012. She has a joint appointment in the Department of Medical Microbiology and Immunology and affiliate appointments in the Department of Medicine and the Department of Biomedical Engineering.

Dr. Huttenlocher is a practicing pediatric rheumatologist and directs the pediatric rheumatology program within the Department of Pediatrics. She is a physician-scientist with expertise in treating autoimmunity and immune dysregulation and is particularly interested in autoinflammatory disease and inherited disorders that alter immunity and inflammation. Dr. Huttenlocher’s research focuses on understanding inflammation and its resolution. Her lab investigates how external cues and cell signaling networks regulate immune cell migration during tissue damage and repair, and how this is altered in human disease. The Huttenlocher Lab uses live imaging to visualize and manipulate leukocyte motility in zebrafish and human cells, uncovering mechanisms that regulate resolution of innate immune inflammation. Her laboratory is also engineering human induced pluripotent stem cells (iPS) to generate human neutrophils that have immunomodulatory functions that can be applied to treatment of patients with uncontrolled infection or cancer. She is recognized internationally for her pioneering studies on cell migration and the use of zebrafish to image inflammation in vivo.

Dr. Huttenlocher has trained over 50 PhD, MD or MD-PhD students and fellows, many of whom are now faculty members and run independent research programs. She is deeply committed to the education of physician-scientists. She co-directed the UW Institute of Clinical and Translational Research’s KL2 training program, which trains and supports junior faculty from diverse backgrounds and disciplines who are actively engaged in translational research and want to develop an independent research program.

Her honors include election to the National Academy of Medicine, American Society of Clinical Investigation (ASCI), and the Association of American Physicians (AAP), where she currently serves on the council. She was named an American Society of Cell Biology fellow and Clare Hall fellow at the University of Cambridge, and she serves as a senior editor at the Journal of Cell Biology.

Trained at Harvard Medical School, Boston Children’s Hospital and the University of California-San Francisco, Dr. Huttenlocher joined the UW–Madison faculty in 1999 in the Department of Pediatrics and served as Associate Director of MSTP from 1999–2012.