Recipients of 2011 UWCCC IIT Awards are Announced
It is the goal of the UWCCC to foster the development of investigator driven clinical research trials which define and develop novel agents and whose designs focus on a translational theme.
A total of 60 translational research applications were submitted in 2011 for the UWCCC/ACS Fall and Spring RFAs, with a total of 18 applications awarded. The UWCCC will again send out solicitations in April and October 2012, which will focus on population health and clinical translational research.
Spring 2011
Analysis of the Tolerogenic Effects of Human NKT Cells in a Novel Humanized Mouse Model of Chronic GVHD
PI: Jenny Gumperz
Co-PI: William Hallett
Characterization of Molecular Signatures Predicting Response to 5-FU-Based Chemotherapy in Mouse Models of Colorectal Cancer
PI: William Schelman
Co-PIs: Richard Halberg, Greg Kennedy, Michael Newton
The Influence of KIR and HLA Genotype on the Response to Rituximab Immunotherapy in ECOG-E4402 Patients with Follicular Lymphoma
PI: Paul Sondel
Co-PIs: Brad Kahl, Erik Ranheim, Jackie Hank, Bartosz Gryzwacz, KyungMann Kim, Amy Erbe, Songwon Seo
Allelic Differences in Target Antigen as a Predictor of Response to Antigen-Specific Anti-Tumor Immunization
PI: Douglas McNeel
Racial/Ethnic Disparities in Pancreatic Cancer Care
PI: Noelle LoConte
Development of Transgene-Free Induced Pluripotent Stem Cells from Primary Human Lymphoma
PI: Igor Slukvin
Co-PIs: David Yang, Gordana Raca
Microscale Culture to Enable the Study of Ovarian Cancer-Macrophage Interactions
PI: Pamela Kreeger
Validation of a Genomics Based Assay for Personalized Treatment of Patients with Recurrent Ovarian Cancer
PI: Christina Kendziorski
Co-PI: Kevin Eng
Decitabine Followed by Total Body Irradiation and a Partially-Matched Bone Marrow Transplant for the Treatment of Advance Leukemia and Myelodysplastic Syndromes
PI: Mark Juckett
Co-PIs: Walter Longo, Ryan Mattison, KyungMann Kim
A High Throughput Method to Identify Functionally Significant SNPs in Breast Cancer Using the SNP-SNAP Microarray
PI: James Shull
Co-PIs: Elizabeth Burnside, Mary Ozers
Fall 2011
Syndecan-based Therapeutics for Head & Neck Cancer
PI: Alan Rapraeger
Co-Inves: Paul Harari
Dual Pathway Inhibition to Treat Myeloproliferative Neoplasms
PI: Jing Zhang
Co-Inves: Ryan Mattison, Mark Juckett
Determination of Fibronectin Involvement In Tumorigenesis-Associated Fibrosis In Two Mouse Models Of Mammary Carcinoma
PI: Deane Mosher
Co-Inves: Patricia Keely, Bianca Thomasini-Johansson, Kevin Eliceiri
Patterns of Oncologist Breast Cancer Follow-Up And Relationship With Outcome
PI: Heather Neuman
Elucidating the Structural Basis of CMV and EBV Protein Kinases for Drug Target
PI: Yongna Xing
Co-Inves: Robert Kalejta, Shannon Kenney
Surveying for Work Limitations and Associated Symptoms in Cancer Patients Receiving Adjuvant Chemotherapy
PI: Amye Tevaarwerk
Co-Inves: Mary Sesto, Noelle LoConte, Kris Kwekkeboom
Identification of Novel Biomarkers for Response to IGF-1R/IR Inhibition In Advanced Breast Cancer
PI: Kari Wisinski
Co-Inves: Jill Kolesar, Wei Huang
The Role of Factor IXa in the Hypercoagulability of Ovarian Cancer
PI: John Sheehan
Co-Inves: Ellen Hartenbach, Songwon Seo
Date Published: 02/09/2012
