Sean Fain Earns Hartwell Award for Cystic Fibrosis Research
Madison, Wisconsin - The quality of life for children with cystic fibrosis has been improving over the years, in part through earlier diagnosis and clinical intervention.
Thanks to a $300,000 Collaboration Award from The Hartwell Foundation, researcher Sean Fain of the University of Wisconsin School of Medicine and Public Health and Dr. Talissa Altes at the University of Virginia will explore 4-D imaging of the lungs in young children in connection with cystic fibrosis.
The hope is that research will allow examination and treatment of children at younger ages than has been possible.
The project grew out of Fain's research that was made possible in part by an earlier Hartwell Investigator Award.
"That was for investigating childhood asthma with magnetic resonance imaging, doing what we call 4-D imaging, which is three-dimensional plus time," says Fain, an associate professor of medical physics.
In that asthma study, Fain and his team worked closely with Dr. Robert Lemanske, a professor of pediatrics and medicine who has been studying the childhood origins of asthma. Lemanske and his team have been following a group of children since birth.
"We had been investigating ventilation and trying to understand early onset of asthma and correlating ventilation defects with known risk factors," Fain says.
Lemanske's group, with its long history, allowed for the imaging results to be correlated with risk factors.
"That provides a level of prediction about the likelihood to develop asthma clinically," Fain says.
Date Published: 03/10/2011