Mutation in common protein triggers tangles, chaos inside brain cells
A pioneer in the study of neural cells revealed how a single mutation affecting the most common protein in a supporting brain cell produces devastating, fibrous globs.
Researchers discover cause for rare genetic blood disorder
An eight-year quest to find the cause of a disease has apparently ended now that scientists at UW–Madison have identified the mutations that produce a form of myelofibrosis, a rare genetic blood disorder.
Clinical prospects for stem cells begin to emerge
Twenty years after the University of Wisconsin–Madison’s James Thomson derived the first human embryonic stem cell lines (ESC), his revolutionary discovery is just beginning to emerge on the clinical landscape.
UW-Madison study is first to link cadmium exposure to lower ability to see contrast
Cadmium exposure may increase the risk for problems with a key component of good vision, according to a new study from the University of Wisconsin School of Medicine and Public Health.
Blockages in nerve-cell protein ‘factory’ implicated in neurodegenerative disease
A molecular basis underlying the neurodegenerative condition hereditary spastic paraplegia (HSP) has been identified in a study by University of Wisconsin School of Medicine and Public Health researchers.
UW to test using MDMA in treatment of severe PTSD
The Department of Family Medicine and Community Health of the UW School of Medicine and Public Health will take part in a multisite Food and Drug Administration-approved Phase III trial investigating MDMA as an adjunct to psychotherapy for the treatment of severe post-traumatic stress disorder (PTSD).
UW researchers discover mechanism controlling zinc that is vital to red blood cell creation
Researchers have uncovered how a trace metal controls the generation of red blood cells, which are critical for life.
UW scientists discover cause of aging-related disease in mice, then reverse its symptoms
In a study published in Aging Cell, researchers at the University of Wisconsin–Madison show that mice making too much of a human protein called AT-1 show signs of early aging and premature death, which are also symptoms of the human disorder progeria.
Researchers trace Parkinson’s damage in the heart
A new way to examine stress and inflammation in the heart will help Parkinson’s researchers test new therapies and explore an unappreciated way the disease puts people at risk of falls and hospitalization.
Review of multiple studies shows early hormone use not associated with cognitive problems in healthy women
Hormone therapy is not associated with cognitive harm for women if therapy begins around the age of menopause in healthy women, according to University of Wisconsin-Madison research presented this week at the 2018 Alzheimer’s Association International Conference (AAIC) in Chicago.
Forgotten molecules find new purpose at Carbone Cancer Center
On a rainy day last fall, chemist Scott Wildman left his office on the UW–Madison campus and drove to a retirement community on the city’s west side to bring 40 years of scientific work out of the dark.
Cell therapy is the future, and Wisconsin is the place, says Jacques Galipeau
Medicine is rapidly approaching a great advance that will augment or replace drugs with human cells for treating a range of intractable conditions, an expert in cell therapy told the Wisconsin Technology Council on June 26.